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GLP-1: what is it and what does it do?

GLP-1 is a hormone your gut produces after eating. It plays a role in your appetite, your feeling of fullness and your blood sugar. GLP-1 medicines mimic that hormone and are prescription-only. Here you can read how GLP-1 works, which medicines exist and how a Soap doctor assesses whether it suits you.

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What is GLP-1?

SMART SCIENCE

GLP-1 stands for glucagon-like peptide-1. It is a gut hormone your body produces after eating, and it plays a role in your appetite and food intake.

A GLP-1 agonist, also called a GLP-1 receptor agonist, is a medicine that resembles that natural hormone. It binds to the same receptor and activates it.

So GLP-1 is not a brand, but the name of the hormone these medicines are based on.

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HOW IT WORKS

How GLP-1 works in your body

After a meal, GLP-1 gives the signal that you are full. The hormone does three things at once:

  • Through your brain it curbs your appetite, so you feel less hungry.

  • Your stomach empties slightly more slowly, so you feel full for longer.

  • Your blood sugar stays more stable.

GLP-1 medicines mimic that effect.

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KNOW YOUR OPTIONS

Which GLP-1 medicines are there?

GLP-1 medicines are prescription-only. Within the Soap Medical Weight Loss programme, our doctors only prescribe medication registered in the EU:

  • Ozempic and Wegovy contain semaglutide, a GLP-1 medicine.

  • Mounjaro contains tirzepatide and acts on two hormone receptors: GLP-1 and GIP.

Which of these weight loss medications suits you is something the doctor decides together with you during the free consult.

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IS IT FOR YOU?

GLP-1 and weight loss: who is it meant for?

GLP-1 medication is not a quick fix and not a replacement for a healthy lifestyle.

Our Medical Weight Loss programme is meant for people with a BMI of 27 or higher. That doesn't mean you automatically get medication: the doctor only prescribes it when that is medically responsible and appropriate.

GLP-1 injection or GLP-1 tablet?

PEN OR PILL

  • Injection: Ozempic, Wegovy and Mounjaro are given with a weekly injection pen.

  • Tablet: Wegovy also comes as a tablet. You take it daily, instead of a weekly injection. Our doctors can prescribe the pill form when this is medically appropriate.

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PERSONAL FIRST

GLP-1 medication at Soap: with a doctor

You start with a free consult, on location or by video. The doctor looks at your health, your BMI and your medical history.

If medication suits you, the doctor sends the prescription to an affiliated pharmacy. After that we plan regular check-ins. There we follow your progress, discuss side effects and adjust the dose.

GLP-1 side effects: what can you notice?

NO SURPRISES

With the GLP-1 medicines Soap prescribes, stomach and bowel complaints are the most common side effects:

  • Nausea

  • Vomiting

  • Diarrhoea

  • Constipation

  • Abdominal pain

These complaints are generally mild to moderate. They occur more often in the period when the dose is increased.

The complete list is in the package leaflet of the medicine. If you have complaints or doubts about your dose, contact your doctor. At Soap we discuss this as standard during the check-ins.

GOOD TO KNOW

Frequently asked questions about GLP-1

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Curious whether GLP-1 suits you?

Book a free consult with a Soap doctor, on location or by video. You discuss your health and your goal, and you hear which approach suits you.